Transdermal administration of drugs is generally limited by the barrier function of the skin.Vesicular systems are one of the most controversial methods for transdermal delivery of active substances.The interest in designing transdermal delivery systems was relaunched after the discovery Accessories of elastic vesicles like transferosomes, ethosome

Abstract Background Thermus thermophilus and Deinococcus radiodurans belong to a distinct bacterial clade but have remarkably different phenotypes.T.thermophilus is a thermophile, which is relatively sensitive to ionizing radiation and desiccation, whereas D.radiodurans is a mesophile, which is highly radiation- and desiccation-resistant.Here we pr

Tinkering with pre-existing genes has long been known as a major CD way to create new genes.Recently, however, motherless protein-coding genes have been found to have emerged de novo from ancestral non-coding DNAs.How these genes originated is not well addressed to date.Here we identified 24 hominoid-specific de novo protein-coding genes with preci

Objectives: The COVID-19 pandemic had a disruptive impact on tuberculosis (TB) and HIV services.We assessed the in-hospital TB diagnostic care among people with HIV (PWH) Hyer Accessories overall and before and during the pandemic.Methods: In this prospective study, adult PWH admitted at three hospitals in Ghana were recruited if they had a positiv

We report two cases of systemic sarcoidosis with atrial flutter as the clinical manifestation.In one patient, who had symptoms of shorter duration, the arrhythmia was no longer inducible after a course of glucocorticoid therapy.Electroanatomical mapping in the other case revealed patchy fibrosis of the left atrial myocardium and Accessories multipl